Article
Association between single nucleotide polymorphisms in the gene for XRCC1 and radiation-induced late toxicity in prostate cancer patients.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Mar 2011
Langsenlehner Tanja, Renner Wilfried, Gerger Armin, Hofmann Günter, Thurner Eva-Maria, Kapp Karin S, Langsenlehner Uwe
Abstract excerpt
BACKGROUND AND PURPOSE: Polymorphisms in genes responsible for DNA damage signaling and repair might modulate DNA repair capacity and, therefore, affect cell and tissue response to radiation and influence individual radiosensitivity. The purpose of the present prospective investigation was to evaluate the association of single nucleotide polymorphisms in XRCC1 with radiation-induced late side effects in prostate...
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