Article
Association of XRCC1 gene polymorphisms with the susceptibility and chromosomal aberration of testicular germ cell tumors.
International journal of oncology - 1 May 2006
Tsuchiya Norihiko, Mishina Mutsuki, Narita Shintaro, Kumazawa Teruaki, Inoue Takamitsu, Horikawa Yohei, Kakinuma Hideaki, Yuasa Takeshi, Matsuura Shinobu, Satoh Shigeru, Ogawa Osamu, Habuchi Tomonori
Abstract excerpt
It is known that many genomic and genetic alterations caused by aging or environmental factors are responsible for cancer development and progression. XRCC1 is involved in the repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. The objective of this study was to investigate the association of genomic alterations and the susceptibility of testicular germ cell tumors...
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