Article
Relationship between the expression of ompF and quinolone resistance in Escherichia coli.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Dec 2009
Kishii Ryuta, Takei Masaya
Abstract excerpt
The outer membrane porin protein, OmpF, is widely found in gram-negative bacteria. It is known that the decreased expression of OmpF causes resistance to multiple antibiotics, including quinolones. In order to characterize the influence of decreased OmpF expression on bacterial growth, the fitness of the ompF and gyrA mutant strain of Escherichia coli selected experimentally with quinolone was compared with that...
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