Article
High-grade mutant OmpF induces decreased bacterial survival rate.
Acta biochimica Polonica - 1 Jan 2014
Zhao Zhi-ping, Liu Ting-ting, Zhang Li, Luo Min, Nie Xin, Li Zai-xin, Pan Yu
Abstract excerpt
OmpF plays very important roles in the influx of antibiotics and bacterial survival in the presence of antibiotics. However, high-grade mutant OmpF and its function in decreasing bacterial survival rate have not been reported to date. In the present study, we cloned a high-grade mutant OmpF (mOmpF) and sequence analysis suggested that over 45 percent of the DNA sequence was significantly mutated, leading to...
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