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Article

Effects of a Mutation in the gyrA Gene on the Virulence of Uropathogenic Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Aug 2015

Sánchez-Céspedes Javier, Sáez-López Emma, Frimodt-Møller N, Vila Jordi, Soto Sara M

Abstract excerpt

Fluoroquinolones are among the drugs most extensively used for the treatment of bacterial infections in human and veterinary medicine. Resistance to quinolones can be chromosome or plasmid mediated. The chromosomal mechanism of resistance is associated with mutations in the DNA gyrase- and topoisomerase IV-encoding genes and mutations in regulatory genes affecting different efflux systems, among others. We...

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Identifiers

PMID: 26014933
DOI: 10.1128/AAC.00665-15
PMCID: PMC4505250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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