Article
Genetics and regulation of outer membrane protein expression by quinolone resistance loci nfxB, nfxC, and cfxB.
Antimicrobial agents and chemotherapy - 1 May 1992
Hooper D C, Wolfson J S, Bozza M A, Ng E Y
Abstract excerpt
Quinolone resistance mutations (cfxB1, marA1, and soxQ1) that reduce porin outer membrane protein OmpF map near 34 min on the Escherichia coli chromosome. Another such mutation, nfxC1, was found in strain KF131 (nfxB, 19 min). nfxC1 and cfxB1 mutants (selected with quinolones) differed slightly b...
Topics
- 4-Quinolones
- Anti-Infective Agents
- Bacterial Outer Membrane Proteins
- Drug Resistance, Microbial
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Mutation