Article
beta-Lactamase expression and outer membrane protein changes in cefpirome-resistant and ceftazidime-resistant gram-negative bacteria.
The Journal of antimicrobial chemotherapy - 1 Aug 1991
Piddock L J, Traynor E A
Abstract excerpt
Twenty-five strains of Enterobacteriaceae (five each of Enterobacter cloacae, Citrobacter freundii, Serratia marcescens, Morganella morganii, and Providencia stuartii) and five strains of Pseudomonas aeruginosa were exposed to various concentrations of cefpirome or ceftazidime in agar. Mutants with a greater than four-fold increase in the MIC were examined for changes in beta-lactamase expression and outer...
Topics
- Bacterial Outer Membrane Proteins
- Ceftazidime
- Cephalosporins
- Enterobacteriaceae
- Microbial Sensitivity Tests
- Mutation
- Pseudomonas aeruginosa
- beta-Lactamases
- Cefpirome
