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Article

Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations.

Journal of bacteriology - 1 Mar 1991

Connolly D M, Winkler M E

Abstract excerpt

Previously, we reported several unusual relationships between the 2-methylthio-N6-(delta 2-isopentenyl)adenosine-37 (ms2i6A-37) tRNA modification and spontaneous mutagenesis in Escherichia coli K-12 (D. M. Connolly and M. E. Winkler, J. Bacteriol. 171:3233-3246, 1989). To confirm and extend these observations, we determined the structure of miaA, which mediates the first step of ms2i6A-37 synthesis, and...

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Identifiers

PMID: 1999389
DOI: 10.1128/jb.173.5.1711-1721.1991
PMCID: PMC207322

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