Article
Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 1996
Slupska M M, Baikalov C, Lloyd R, Miller J H
Abstract excerpt
We have previously described the mutator alleles mutA and mutC, which map at 95 minutes and 42 minutes, respectively, on the Escherichia coli genetic map and which stimulate transversions; the A.T-->T.A and G.C-->T.A substitutions are the most prominent. In this study we show that both mutA and m...
Topics
- Alleles
- Amino Acid Sequence
- Aspartic Acid
- Base Composition
- Base Sequence
- Cloning, Molecular
- DNA Primers
- Escherichia coli
- Genes, Bacterial
- Genetic Complementation Test
- Glycine
- Molecular Sequence Data
- Mutagenesis
- Plasmids
- Polymerase Chain Reaction
- RNA, Transfer
- RNA, Transfer, Gly
- Restriction Mapping