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Article

The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates.

Journal of bacteriology - 1 Jun 1998

Persson B C, Olafsson O, Lundgren H K, Hederstedt L, Björk G R

Abstract excerpt

The modified nucleoside 2-methylthio-N-6-isopentenyl adenosine (ms2i6A) is present in position 37 (adjacent to and 3' of the anticodon) of tRNAs that read codons beginning with U except tRNA(i.v. Ser) in Escherichia coli. In Salmonella typhimurium, 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenos...

Topics

Chromosome Mapping
Citric Acid Cycle
Fumarates
Genes, Bacterial
Genetic Complementation Test
Isopentenyladenosine
Malates
Mutation
Phenotype
RNA, Transfer
Salmonella typhimurium
Succinic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9620964
DOI: 10.1128/JB.180.12.3144-3151.1998
PMCID: PMC107815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9620964-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates.PMID 9620964Read ↗

The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA.Semantic proximity Read ↗

Modification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxesSemantic proximity Read ↗

Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri.Semantic proximity Read ↗

The cysteine desulfurase IscS is required for synthesis of all five thiolated nucleosides present in tRNA from Salmonella enterica serovar typhimurium.Semantic proximity Read ↗

7-Methylguanosine Modifications in tRNASemantic proximity Read ↗

Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs.Semantic proximity Read ↗

Targeting of mitochondrial and cytosolic substrates of tRNA isopentenyltransferases: selection of differential tRNA-i6A37 identity subsetsSemantic proximity Read ↗

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Amino acid residues of the Escherichia coli tRNA(m5U54)methyltransferase (TrmA) critical for stability, covalent binding of tRNA and enzymatic activity.Semantic proximity Read ↗

Host mutations (miaA and rpsL) reduce tetracycline resistance mediated by Tet(O) and Tet(M).Semantic proximity Read ↗

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