The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA.

doi:10.1128/jb.177.8.1967-1975.1995

Article

The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA.

Journal of bacteriology - 1 Apr 1995

Esberg B, Björk G R

Abstract excerpt

A Salmonella typhimurium LT2 mutant which harbors a mutation (miaB2508::Tn10dCm) that results in a reduction in the activities of the amber suppressors supF30 (tRNA(CUATyr)), supD10 (tRNA(CUASer)), and supJ60 (tRNA(CUALeu)) was isolated. The mutant was deficient in the methylthio group (ms2) of N...

Topics

Anticodon
Base Sequence
Codon
Genes, Bacterial
Isopentenyladenosine
Molecular Sequence Data
Molecular Structure
Mutation
RNA, Bacterial
RNA, Transfer, Amino Acid-Specific
Salmonella typhimurium
Suppression, Genetic

The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA.

Abstract excerpt

Topics

Discuss the evidence