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Article

Expression of candidate tumor suppressor gene ING2 is lost in non-small cell lung carcinoma.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2010

Ythier Damien, Brambilla Elisabeth, Binet Romuald, Nissou Damien, Vesin Aurélien, de Fraipont Florence, Moro-Sibilot Denis, Lantuejoul Sylvie, Brambilla Christian, Gazzeri Sylvie, Pedeux Rémy

Abstract excerpt

ING2 is a candidate tumor suppressor gene involved in cell cycle control, apoptosis and senescence. Furthermore, we have recently shown that loss of ING2 expression is associated with increased genome instability. We investigated its status in a series of 120 non-small cell lung cancer (NSCLC) by using immunohistochemistry (IHC). The results showed that ING2 protein expression is downregulated in more than 50% of...

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Source

Identifiers

PMID: 19962781
DOI: 10.1016/j.lungcan.2009.11.006

Genes

ING2
ADK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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