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Article

The new tumor suppressor genes ING: Genomic structure and status in cancer

17 Jul 2008

Abstract excerpt

The Inhibitor of Growth 1 (ING1) gene has been identified and characterized as a Type-II tumor suppressor gene (TSG). Subsequently, 4 additional members of the family were identified by homology search. ING proteins contain a nuclear localization sequence (NLS) and a plant homeo domain (PHD) finger motif in their C-terminus. These proteins are involved in numerous signaling pathways especially in 2 tumor...

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PMID: 18636562
DOI: 10.1002/ijc.23790

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The new tumor suppressor genes ING: Genomic structure and status in cancerPMID 18636562Read ↗

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