Article
LATS2 tumour specific mutations and down-regulation of the gene in non-small cell carcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Jun 2009
Strazisar Mojca, Mlakar Vid, Glavac Damjan
Abstract excerpt
LATS2 is a new member of the LATS tumour suppressor family. The human LATS2 gene is located at chromosome 13q11-12, a hot spot (67%) for loss of heterozygosity (LOH) in non-small cell lung cancer (NSCLC). We screened 129 non-small cell lung cancer samples and 13 lung cancer cell lines, initially...
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