Article
Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer.
Cancer science - 1 Mar 2008
Gunduz Mehmet, Beder Levent Bekir, Gunduz Esra, Nagatsuka Hitoshi, Fukushima Kunihiro, Pehlivan Davut, Cetin Eren, Yamanaka Noboru, Nishizaki Kazunori, Shimizu Kenji, Nagai Noriyuki
Abstract excerpt
Although many clinical and pathological prognostic factors such as tumor stage and lymph-node involvement have been described, to date no reliable or clinically applicable marker or tumor aggressiveness has been identified for head and neck cancer. In an attempt to identify such a molecular prognostic marker, we analyzed the mRNA expression status of ING3 by quantitative reverse transcription-polymerase chain...
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