Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Notch mRNA expression in Drosophila embryos is negatively regulated at the level of mRNA 3' processing.

PloS one - 30 Nov 2009

Shepherd Andrew K, Singh Ravinder, Wesley Cedric S

Abstract excerpt

Notch receptor regulates differentiation of almost all tissues and organs during animal development. Many mechanisms function at the protein level to finely regulate Notch activity. Here we provide evidence for Notch regulation at an earlier step - mRNA 3' processing. Processing at the Notch cons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cloning, Molecular
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Gene Expression Regulation, Developmental

Share to Polyadenylation

Share to Receptors, Notch

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 19956683
DOI: 10.1371/journal.pone.0008063
PMCID: PMC2778129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19956683-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch mRNA expression in Drosophila embryos is negatively regulated at the level of mRNA 3' processing.PMID 19956683Read ↗

U7 snRNA mutations in Drosophila block histone pre-mRNA processing and disrupt oogenesis.Semantic proximity Read ↗

Loss of PTB or negative regulation of Notch mRNA reveals distinct zones of Notch and actin protein accumulation in Drosophila embryo.Semantic proximity Read ↗

The polyadenosine RNA binding protein Nab2 regulates alternative splicing and intron retention during <i>Drosophila melanogaster</i> brain developmentSemantic proximity Read ↗

Differences and similarities between Drosophila and mammalian 3' end processing of histone pre-mRNAs.Semantic proximity Read ↗

In vivo characterization of the Drosophila mRNA 3' end processing core cleavage complex.Semantic proximity Read ↗

Loss of the histone pre-mRNA processing factor stem-loop binding protein in Drosophila causes genomic instability and impaired cellular proliferation.Semantic proximity Read ↗

Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression.Semantic proximity Read ↗

Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation.Semantic proximity Read ↗

Identification of alternative splicing regulators by RNA interference in Drosophila.Semantic proximity Read ↗

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.Semantic proximity Read ↗

Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster.Semantic proximity Read ↗

A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.