Differences and similarities between Drosophila and mammalian 3' end processing of histone pre-mRNAs.

doi:10.1261/rna.2179305

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Differences and similarities between Drosophila and mammalian 3' end processing of histone pre-mRNAs.

RNA (New York, N.Y.) - 1 Dec 2005

Dominski Zbigniew, Yang Xiao-Cui, Purdy Mathew, Marzluff William F

Abstract excerpt

We used nuclear extracts from Drosophila Kc cells to characterize 3' end processing of Drosophila histone pre-mRNAs. Drosophila SLBP plays a critical role in recruiting the U 7 snRNP to the pre-mRNA and is essential for processing all five Drosophila histone pre-mRNAs. The Drosophila processing machinery strongly prefers cleavage after a fourth nucleotide following the stem-loop and favors an adenosine over...

Topics

Animals
Base Sequence
Cell Nucleus
Drosophila
Drosophila Proteins
Histones
Mice
Molecular Sequence Data
Mutation
RNA Precursors
RNA Processing, Post-Transcriptional
RNA-Binding Proteins
Ribonucleoprotein, U7 Small Nuclear
Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 16251385
DOI: 10.1261/rna.2179305
PMCID: PMC1370872

Genes

SLBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics