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Article

In vivo characterization of the Drosophila mRNA 3' end processing core cleavage complex.

RNA (New York, N.Y.) - 1 Aug 2015

Michalski Daniel, Steiniger Mindy

Abstract excerpt

A core cleavage complex (CCC) consisting of CPSF73, CPSF100, and Symplekin is required for cotranscriptional 3' end processing of all metazoan pre-mRNAs, yet little is known about the in vivo molecular interactions within this complex. The CCC is a component of two distinct complexes, the cleavage/polyadenylation complex and the complex that processes nonpolyadenylated histone pre-mRNAs. RNAi-depletion of CCC...

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Identifiers

PMID: 26081560
DOI: 10.1261/rna.049551.115
PMCID: PMC4509931

Genes

SLBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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