Article
New classification of the shared epitope in rheumatoid arthritis: impact on the production of various anti-citrullinated protein antibodies.
Rheumatology (Oxford, England) - 1 Jan 2010
Gyetvai Agnes, Szekanecz Zoltán, Soós Lilla, Szabó Zoltán, Fekete Andrea, Kapitány Anikó, Teodorescu Marius, Sipka Sándor, Szegedi Gyula, Lakos Gabriella
Abstract excerpt
OBJECTIVE: HLA-DR [shared epitope (SE)] alleles have recently been re-classified into S1, S2, S3P and S3D groups. S2 and S3P have been associated with increased risk for RA. We assessed the impact of S1, S2, S3P and S3D alleles on anti-citrullinated protein antibody (ACPA) production. Instead of...
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