Brief Report: Main Contribution of DRB1*04:05 Among the Shared Epitope Alleles and Involvement of DRB1 Amino Acid Position 57 in Association With Joint Destruction in Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis.

doi:10.1002/art.39105

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Brief Report: Main Contribution of DRB1*04:05 Among the Shared Epitope Alleles and Involvement of DRB1 Amino Acid Position 57 in Association With Joint Destruction in Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Jul 2015

Terao Chikashi, Yano Koichiro, Ikari Katsunori, Furu Moritoshi, Yamakawa Noriyuki, Yoshida Shinji, Hashimoto Motomu, Ito Hiromu, Fujii Takao, Ohmura Koichiro, Yurugi Kimiko, Miura Yasuo, Maekawa Taira, Taniguchi Atsuo, Momohara Shigeki, Yamanaka Hisashi, Mimori Tsuneyo, Matsuda Fumihiko

Abstract excerpt

OBJECTIVE: The shared epitope is associated with increased joint destruction in rheumatoid arthritis (RA) as well as susceptibility to RA and the production of anti-citrullinated protein antibody (ACPA). However, previous studies addressing whether the association of the shared epitope with joint destruction is independent of ACPA have shown different results in different populations. Different allele...

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PMID: 25777156
DOI: 10.1002/art.39105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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