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Article

Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.

Arthritis and rheumatism - 1 Dec 2005

Irigoyen Patricia, Lee Annette T, Wener Mark H, Li Wentian, Kern Marlena, Batliwalla Franak, Lum Raymond F, Massarotti Elena, Weisman Michael, Bombardier Claire, Remmers Elaine F, Kastner Daniel L, Seldin Michael F, Criswell Lindsey A, Gregersen Peter K

Abstract excerpt

OBJECTIVE: To examine the association between HLA-DRB1 alleles and the production of anti-cyclic citrullinated peptide (anti-CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). METHODS: We studied 1,723 Caucasian RA patients enrolled in the North American Rheumatoid Arthritis Consortium (NARAC) family cohort and the Study of New Onset Rheumatoid Arthritis (SONORA) cohort....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16320316
DOI: 10.1002/art.21419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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