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Article

The impact of HLA-DRB alleles on the subclass titres of antibodies against citrullinated peptides.

Rheumatology (Oxford, England) - 1 Oct 2010

Engelmann Robby, Eggert Martin, Neeck Gunther, Mueller-Hilke Brigitte

Abstract excerpt

OBJECTIVES: The association between HLA-DR haplotypes and RA have been well established. However, the molecular mechanisms of how HLA mediates susceptibility and/or progression of the disease remain elusive. We therefore turned to the RA-specific antibodies directed against citrullinated peptide antigens (ACPAs) and investigated the association between HLA-DRB1 shared epitope (SE) alleles and the IgG subclass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20584722
DOI: 10.1093/rheumatology/keq179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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