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Article

Information-theoretic gene-gene and gene-environment interaction analysis of quantitative traits.

BMC genomics - 4 Nov 2009

Chanda Pritam, Sucheston Lara, Liu Song, Zhang Aidong, Ramanathan Murali

Abstract excerpt

BACKGROUND: The purpose of this research was to develop a novel information theoretic method and an efficient algorithm for analyzing the gene-gene (GGI) and gene-environmental interactions (GEI) associated with quantitative traits (QT). The method is built on two information-theoretic metrics, the k-way interaction information (KWII) and phenotype-associated information (PAI). The PAI is a novel information...

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Identifiers

PMID: 19889230
DOI: 10.1186/1471-2164-10-509
PMCID: PMC2779196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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