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Article

Detecting genetic effects on phenotype variability to capture gene-by-environment interactions: a systematic method comparison.

G3 (Bethesda, Md.) - 3 Apr 2024

Zhang Xiaopu, Bell Jordana T

Abstract excerpt

Genetically associated phenotypic variability has been widely observed across organisms and traits, including in humans. Both gene-gene and gene-environment interactions can lead to an increase in genetically associated phenotypic variability. Therefore, detecting the underlying genetic variants, or variance Quantitative Trait Loci (vQTLs), can provide novel insights into complex traits. Established approaches to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38289865
DOI: 10.1093/g3journal/jkae022
PMCID: PMC10989912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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