Article
Mutual information for testing gene-environment interaction.
PloS one - 1 Jan 2009
Wu Xuesen, Jin Li, Xiong Momiao
Abstract excerpt
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved. In this report, we define gene-environment interactions as a stochastic dependence in the context of the effects of the genetic and environmental risk factors on the cause of phenotypic variation among...
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