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Article

Comparison of information-theoretic to statistical methods for gene-gene interactions in the presence of genetic heterogeneity.

BMC genomics - 3 Sept 2010

Sucheston Lara, Chanda Pritam, Zhang Aidong, Tritchler David, Ramanathan Murali

Abstract excerpt

BACKGROUND: Multifactorial diseases such as cancer and cardiovascular diseases are caused by the complex interplay between genes and environment. The detection of these interactions remains challenging due to computational limitations. Information theoretic approaches use computationally efficient directed search strategies and thus provide a feasible solution to this problem. However, the power of information...

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Identifiers

PMID: 20815886
DOI: 10.1186/1471-2164-11-487
PMCID: PMC2996983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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