Article

Incorporating additive genetic effects and full LD information to discover genome-level gene-environment interactions with summary statistics of complex traits

2024-09-26

Abstract excerpt

<title>Abstract</title> <p>Uncovering environmental factors interacting with genetic factors to influence complex traits is important in genetic epidemiology and disease etiology. Existing methods examining gene-environment (G\(\:\times\:\)E) interactions either test G\(\:\times\:\)E interaction for each genetic variant individually, ignoring correlations with additive genetic effects, or use only partial informa...

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Literature Corpus work: 98f5bbbf-32b6-5285-a972-d50a41e71a1b
DOI: 10.21203/rs.3.rs-4979809/v1

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