The interaction index, a novel information-theoretic metric for prioritizing interacting genetic variations and environmental factors.

doi:10.1038/ejhg.2009.38

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Article

The interaction index, a novel information-theoretic metric for prioritizing interacting genetic variations and environmental factors.

European journal of human genetics : EJHG - 1 Oct 2009

Chanda Pritam, Sucheston Lara, Zhang Aidong, Ramanathan Murali

Abstract excerpt

We developed an information-theoretic metric called the Interaction Index for prioritizing genetic variations and environmental variables for follow-up in detailed sequencing studies. The Interaction Index was found to be effective for prioritizing the genetic and environmental variables involved in GEI for a diverse range of simulated data sets. The metric was also evaluated for a 103-SNP Crohn's disease dataset...

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PMID: 19293841
DOI: 10.1038/ejhg.2009.38
PMCID: PMC2952438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.