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Article

Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2009

Huang Hsuan-Ying, Li Shau-Hsuan, Yu Shih-Chen, Chou Fong-Fu, Tzeng Ching-Cherng, Hu Tsung-Hui, Uen Yih-Huei, Tian Yu-Fang, Wang Yu-Hui, Fang Fu-Min, Huang Wen-Wei, Wei Yu-Ching, Wu Jing-Mei, Li Chien-Feng

Abstract excerpt

PURPOSE: Chromosome 9 is frequently deleted in high-risk gastrointestinal stromal tumors (GISTs), whereas its specific tumor suppressor genes (TSGs) are less understood. We did an integrative study of MTAP gene at 9p21 to analyze its implication in GISTs. EXPERIMENTAL DESIGN: To search TSGs on chromosome 9, we used ultrahigh-resolution array comparative genomic hybridization to profile DNA copy number alterations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19887491
DOI: 10.1158/1078-0432.CCR-09-1511

Genes

MTAP
KIT
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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