Article
Expression profiling of GIST: CD133 is associated with KIT exon 11 mutations, gastric location and poor prognosis.
International journal of cancer - 1 Sept 2011
Arne Gabriella, Kristiansson Erik, Nerman Olle, Kindblom Lars-Gunnar, Ahlman Håkan, Nilsson Bengt, Nilsson Ola
Abstract excerpt
In gastrointestinal stromal tumors (GISTs), KIT exon 11 deletions are associated with poor prognosis. The aim of this study was to determine the gene expression profiles of GISTs carrying KIT exon 11 deletions and to identify genes associated with poor prognosis. Expression profiling was performed on nine tumors with KIT exon 11 deletions and 7 without KIT exon 11 mutations using oligonucleotide microarrays. In...
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