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Article

Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions.

Biology of the cell - 14 Jan 2010

Dumbauld David W, Michael Kristin E, Hanks Steven K, García Andrés J

Abstract excerpt

BACKGROUND INFORMATION: FAK (focal adhesion kinase), an essential non-receptor tyrosine kinase, plays pivotal roles in migratory responses, adhesive signalling and mechanotransduction. FAK-dependent regulation of cell migration involves focal adhesion turnover dynamics as well as actin cytoskeleton polymerization and lamellipodia protrusion. Whereas roles for FAK in migratory and mechanosensing responses have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19883375
DOI: 10.1042/BC20090104
PMCID: PMC4915345

Genes

VCL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions.PMID 19883375Read ↗

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Control of motile and invasive cell phenotypes by focal adhesion kinase.Semantic proximity Read ↗

Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion.Semantic proximity Read ↗

Dystrophin missense mutations alter focal adhesion tension and mechanotransduction.Semantic proximity Read ↗

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