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Article

Integrin-mediated adhesion maintains sarcomeric integrity.

Developmental biology - 1 Feb 2010

Perkins Alexander D, Ellis Stephanie J, Asghari Parisa, Shamsian Arash, Moore Edwin D W, Tanentzapf Guy

Abstract excerpt

Integrin-mediated adhesion to the ECM is essential for normal development of animal tissues. During muscle development, integrins provide the structural stability required to construct such a highly tensile, force generating tissue. Mutations that disrupt integrin-mediated adhesion in skeletal muscles give rise to a myopathy in humans and mice. To determine if this is due to defects in formation or defects in...

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Identifiers

PMID: 19879257
DOI: 10.1016/j.ydbio.2009.10.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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