Article

Type IV collagen is essential for proper function of integrin-mediated adhesion in <i>Drosophila</i> muscle fibers

2018-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Congenital muscular dystrophy (CMD), a subgroup of myopathies and a genetically and clinically heterogeneous group of inherited muscle disorders is characterized by progressive muscle weakness, fiber size variability, fibrosis, clustered necrotic fibers, and central myonuclei present in regenerating muscle. Type IV collagen ( COL4A1 ) mutations have recently been identified in patients with int...

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Literature Corpus work: 21b37730-1f30-59c3-82c0-87cbbc3b1933
DOI: 10.1101/318337

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