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Article

Distinct developmental roles for direct and indirect talin-mediated linkage to actin.

Developmental biology - 1 Sept 2010

Franco-Cea Ari, Ellis Stephanie J, Fairchild Michael J, Yuan Lin, Cheung Tsz Ying Sylvia, Tanentzapf Guy

Abstract excerpt

Transmembrane adhesion receptors, such as integrins, mediate cell adhesion by interacting with intracellular proteins that connect to the cytoskeleton. Talin, one such linker protein, is essential to connect extracellular matrix-bound integrins to the cytoskeleton. Talin can connect to the cytoskeleton either directly, through its actin-binding motifs, or indirectly, by recruiting other actin-binding proteins....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20599891
DOI: 10.1016/j.ydbio.2010.06.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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