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Article

Tensin stabilizes integrin adhesive contacts in Drosophila.

Developmental cell - 1 Mar 2004

Torgler Catherine N, Narasimha Maithreyi, Knox Andrea L, Zervas Christos G, Vernon Matthew C, Brown Nicholas H

Abstract excerpt

We report the functional characterization of the Drosophila ortholog of tensin, a protein implicated in linking integrins to the cytoskeleton and signaling pathways. A tensin null was generated and is viable with wing blisters, a phenotype characteristic of loss of integrin adhesion. In tensin mutants, mechanical abrasion is required during wing expansion to cause wing blisters, suggesting that tensin strengthens...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15030759
DOI: 10.1016/s1534-5807(04)00055-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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