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Article

Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila.

eLife - 20 Jul 2018

Green Hannah J, Griffiths Annabel Gm, Ylänne Jari, Brown Nicholas H

Abstract excerpt

We use the myotendinous junction of Drosophila flight muscles to explore why many integrin associated proteins (IAPs) are needed and how their function is coordinated. These muscles revealed new functions for IAPs not required for viability: Focal Adhesion Kinase (FAK), RSU1, tensin and vinculin. Genetic interactions demonstrated a balance between positive and negative activities, with vinculin and tensin...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30028294
DOI: 10.7554/eLife.35783
PMCID: PMC6092120

Genes

RSU1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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