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Article

A role for integrin in the formation of sarcomeric cytoarchitecture.

Cell - 2 Nov 1990

Volk T, Fessler L I, Fessler J H

Abstract excerpt

We propose that integrins help to coordinate the differentiation of the internal, sarcomeric cytoarchitecture of a muscle fiber with its immediate environment and are essential for correct integration of muscle cells into tissue. We found that integrin alpha PS2 beta PS accumulated at contact regions of Drosophila embryo cells cultured in D-22 medium on Drosophila laminin. Myotubes formed, but subsequent addition...

Topics

Animals
Cell Differentiation
Cells, Cultured
Drosophila
Embryo, Nonmammalian
Fibronectins
Gastrula
Integrins
Laminin
Microscopy, Electron
Muscles
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organ Culture Techniques

Sarcomeres

Source

Identifiers

PMID: 2225065
DOI: 10.1016/0092-8674(90)90449-o

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2225065-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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