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Article

Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

BMC medical genetics - 30 Oct 2009

Chen Suet Nee, Cilingiroglu Mehmet, Todd Josh, Lombardi Raffaella, Willerson James T, Gotto Antonio M, Ballantyne Christie M, Marian A J

Abstract excerpt

BACKGROUND: Plasma level of high-density lipoprotein-cholesterol (HDL-C), a heritable trait, is an important determinant of susceptibility to atherosclerosis. Non-synonymous and regulatory single nucleotide polymorphisms (SNPs) in genes implicated in HDL-C synthesis and metabolism are likely to influence plasma HDL-C, apolipoprotein A-I (apo A-I) levels and severity of coronary atherosclerosis. METHODS: We...

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Source

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Identifiers

PMID: 19878569
DOI: 10.1186/1471-2350-10-111
PMCID: PMC2775733

Genes

APOA5
APOC2
CETP
LIPC
LPL
APOA2
SOAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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