Article
The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis.
BMC cardiovascular disorders - 27 Jan 2009
Chen Suet Nee, Ballantyne Christie M, Gotto Antonio M, Marian Ali J
Abstract excerpt
BACKGROUND: Case-control Genome-Wide Association Studies (GWAS) have identified single nucleotide polymorphisms (SNPs) at the 9p21 locus as risk factors for coronary artery disease (CAD). The locus does not contain a clear candidate gene. Hence, the results of GWAS have raised an intense interest in delineating the basis for the observed association. We analyzed association of 4 SNPs at the 9p21 locus with the...
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