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Article

Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

Lipids in health and disease - 1 Dec 2009

Ronald James, Rajagopalan Ramakrishnan, Ranchalis Jane E, Marshall Julieann K, Hatsukami Thomas S, Heagerty Patrick J, Jarvik Gail P

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNPs) affecting high density lipoprotein (HDL) or low density lipoprotein (LDL) cholesterol levels; these SNPs may contribute to the genetic basis of vascular diseases. RESULTS: We assessed the impact of 34 SNPs at 23 loci on dyslipidemia, key lipid sub-phenotypes, and severe carotid artery disease (CAAD) in a...

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Share to Carotid Artery Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19951432
DOI: 10.1186/1476-511X-8-52
PMCID: PMC2794863

Genes

APOE
CELSR2
PSRC1
TOMM40

Provenance

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