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Article

Functional Variant in the SLC22A3-LPAL2-LPA Gene Cluster Contributes to the Severity of Coronary Artery Disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2016

Wang Long, Chen Juan, Zeng Ying, Wei Jie, Jing Jinjin, Li Ge, Su Li, Tang Xiaojun, Wu Tangchun, Zhou Li

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies have identified that genetic variants in the SLC22A3-LPAL2-LPA gene cluster influence plasma lipoprotein(a) [Lp(a)] concentration. However, the association between this gene cluster and the severity of coronary artery disease (CAD), especially the potential underlying mechanism, remains unclear. The purpose of this study was to investigate the association between...

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Identifiers

PMID: 27417586
DOI: 10.1161/ATVBAHA.116.307311

Genes

CAD
LPA

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