Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.

doi:10.1016/S0140-6736(10)60545-4

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Article

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.

Lancet (London, England) - 8 May 2010

Sarwar Nadeem, Sandhu Manjinder S, Ricketts Sally L, Butterworth Adam S, Di Angelantonio Emanuele, Boekholdt S Matthijs, Ouwehand Willem, Watkins Hugh, Samani Nilesh J, Saleheen Danish, Lawlor Debbie, Reilly Muredach P, Hingorani Aroon D, Talmud Philippa J, Danesh John

Abstract excerpt

BACKGROUND: Whether triglyceride-mediated pathways are causally relevant to coronary heart disease is uncertain. We studied a genetic variant that regulates triglyceride concentration to help judge likelihood of causality. METHODS: We assessed the -1131T>C (rs662799) promoter polymorphism of the apolipoprotein A5 (APOA5) gene in relation to triglyceride concentration, several other risk factors, and risk of...

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Identifiers

PMID: 20452521
DOI: 10.1016/S0140-6736(10)60545-4
PMCID: PMC2867029

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APOA5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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