Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk.

Carcinogenesis - 1 Dec 2009

Terry Kathryn L, Tworoger Shelley S, Gates Margaret A, Cramer Daniel W, Hankinson Susan E

Abstract excerpt

Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibit apoptosis. In vitro studies show that IGF1 increases ovarian cell growth and invasive potential, suggesting a role for the IGF1 pathway in ovarian cancer etiology. We evaluated genetic variation in the IGF1, IGFBP1 and IGFBP3 genes in relation to ovarian cancer risk by genotyping 29 haplotype-tagging single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Haplotypes
Share to Insulin-Like Growth Factor Binding Protein 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insulin-Like Growth Factor Binding Protein 3

Share to Insulin-Like Growth Factor I

Share to Odds Ratio

Share to Ovarian Neoplasms

Share to Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 19858071
DOI: 10.1093/carcin/bgp257
PMCID: PMC2792318

Genes

IGF1
IGFBP3
NHS
IGFBP1
IGFBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk.PMID 19858071Read ↗

IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).Semantic proximity Read ↗

Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk.Semantic proximity Read ↗

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk.Semantic proximity Read ↗

IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.Semantic proximity Read ↗

Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study.Semantic proximity Read ↗

Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.Semantic proximity Read ↗

Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort.Semantic proximity Read ↗

IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families.Semantic proximity Read ↗

A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians.Semantic proximity Read ↗

Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.Semantic proximity Read ↗

Association of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women.Semantic proximity Read ↗

Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.