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Article

Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk.

Carcinogenesis - 1 Dec 2009

Terry Kathryn L, Tworoger Shelley S, Gates Margaret A, Cramer Daniel W, Hankinson Susan E

Abstract excerpt

Insulin-like growth factor (IGF) 1 and its binding proteins foster cellular proliferation and inhibit apoptosis. In vitro studies show that IGF1 increases ovarian cell growth and invasive potential, suggesting a role for the IGF1 pathway in ovarian cancer etiology. We evaluated genetic variation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19858071
DOI: 10.1093/carcin/bgp257
PMCID: PMC2792318

Genes

IGF1
IGFBP3
NHS
IGFBP1
IGFBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19858071-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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