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Article

IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families.

Breast cancer research and treatment - 1 Jun 2011

Rosendahl Ann H, Hietala Maria, Henningson Maria, Olsson Håkan, Jernström Helena

Abstract excerpt

The insulin-like growth factor (IGF) pathway has been implicated as risk modifier in premenopausal breast cancer. In this study, associations between single nucleotide polymorphisms (SNPs) and diplotypes in the IGFBP1 and IGFBP3 genes and circulating IGFBP-3 levels, BRCA family status and breast cancer among women from high-risk breast cancer families were investigated. Nine IGFBP1 and IGFBP3 SNPs were genotyped...

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Source

Identifiers

PMID: 21140206
DOI: 10.1007/s10549-010-1277-1

Genes

IGFBP1
IGFBP3
BRCA2
BRCA1
GCG
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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