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Article

Association of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women.

PloS one - 1 Jan 2014

Kang Han-Sung, Ahn Sei Hyun, Mishra Siddhartha Kumar, Hong Kyeong-Man, Lee Eun Sook, Shin Kyung Hwan, Ro Jungsil, Lee Keun Seok, Kim Mi Kyung

Abstract excerpt

The insulin-like growth factor (IGF) signaling pathway plays an important role in cancer biology. The IGF 1 receptor (IGF1R) overexpression has been associated with a number of hematological neoplasias and solid tumors including breast cancer. However, molecular mechanism involving IGF1R in carcinogenic developments is clearly not known. We investigated the genetic variations across the IGF1R polymorphism and the...

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PMID: 24392142
DOI: 10.1371/journal.pone.0084532
PMCID: PMC3879335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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