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Article

Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk.

Gynecologic oncology - 1 Feb 2011

McGrath Monica, Lee I-Min, Buring Julie, De Vivo Immaculata

Abstract excerpt

OBJECTIVE: The insulin-like growth factor (IGF) pathway plays a critical role in the growth and development of the uterus and is believed to function as a mediator of steroid hormone actions in the endometrium. The local expression of genes encoding IGFs and IGF-binding proteins (IGFBPs) is important in determining IGF bioactivity in the uterus. Genetic variation in key genes within the IGF pathway may influence...

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Source

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Identifiers

PMID: 21078522
DOI: 10.1016/j.ygyno.2010.10.012
PMCID: PMC3238452

Genes

IGFBP1
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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