Article
Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study.
Malaria journal - 17 May 2012
Omar Ahmeddin H, Yasunami Michio, Yamazaki Akiko, Shibata Hiroki, Ofori Michael F, Akanmori Bartholomew D, Shuaibu Mohammed Nasir, Kikuchi Mihoko, Hirayama Kenji
Abstract excerpt
BACKGROUND: In areas mesoendemic for malaria transmission, symptomatic individuals play a significant role as reservoirs for malaria infection. Understanding the pathogenesis of symptomatic malaria is important in devising tools for augmenting malaria control. In this study, the effect of TLR9 polymorphisms on susceptibility to symptomatic malaria was investigated among Ghanaian children. METHODS: Four hundred...
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