Article

scRNA-Seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria

2023-06-05

Abstract excerpt

Malaria causes significant morbidity and mortality worldwide, disproportionately impacting sub-Saharan Africa. Disease phenotypes associated with malarial infection can vary widely, from asymptomatic to life-threatening. To date, prevention efforts, particularly those related to vaccine development, have been hindered by an incomplete understanding of which factors impact host immune responses resulting in these d...

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Literature Corpus work: f543c60e-de68-5424-9f33-516022b6ca63
DOI: 10.1101/2023.06.02.23290878

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