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Selenium supplementation reduced oxidative DNA damage in adnexectomized BRCA1 mutations carriers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2009

Dziaman Tomasz, Huzarski Tomasz, Gackowski Daniel, Rozalski Rafal, Siomek Agnieszka, Szpila Anna, Guz Jolanta, Lubinski Jan, Wasowicz Wojciech, Roszkowski Krzysztof, Olinski Ryszard

Abstract excerpt

Some experimental evidence suggests that BRCA1 plays a role in repair of oxidative DNA damage. Selenium has anticancer properties that are linked with protection against oxidative stress. To assess whether supplementation of BRCA1 mutation carriers with selenium have a beneficial effect concerning oxidative stress/DNA damage in the present double-blinded placebo control study, we determined 8-oxodG level in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19843683
DOI: 10.1158/1055-9965.EPI-09-0529

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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