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Article

DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.

Mutation research - 9 Aug 2001

Janssen K, Schlink K, Götte W, Hippler B, Kaina B, Oesch F

Abstract excerpt

8-oxoguanine DNA glycosylase 1 (OGG1) is a DNA repair enzyme that excises 7,8-dihydro-8-oxoguanine (8oxoG) from DNA. Since 8oxoG is a highly mispairing lesion, decreased OGG1 expression level could lead to a higher background mutation frequency and could possibly increase the cancer risk of an individual under oxidative stress. In order to analyse the natural variation of OGG1, we measured the DNA repair activity...

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Source

Identifiers

PMID: 11459633
DOI: 10.1016/s0921-8777(01)00096-9

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.PMID 11459633Read ↗

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Influence of the OGG1 Ser326Cys polymorphism on oxidatively damaged DNA and repair activity.Semantic proximity Read ↗

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